We are experiencing the effects of the triple planetary crisis—climate change, loss of nature, and pollution—aggravated by plastic pollution. Despite widespread global awareness of the adverse effects of plastic pollution, its ongoing increase remains persistent, with an annual increase in plastic consumption and incorrect disposal contributing to this serious problem. In 2022, 175 nations agreed to begin negotiations by the end of 2024 on a binding international agreement to control the life cycle of plastics, including preventing marine pollution. To ensure the efficacy of the Global Plastics Treaty for mitigating plastic pollution, the extensive participation of researchers is imperative. The literature focuses on efforts in line with ongoing negotiations. In this study, a systematic review of the Global Plastics Treaty was conducted. The analyzed literature mainly focuses on the adverse effects of plastic pollution, legislation, governance, and the economy. The resulting comprehensive overview of the subject can support ongoing negotiations and guide future research about the Global Plastics Treaty.