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1 results

  • Cough after laryngeal herpes zoster: a new aspect of post-herpetic sensory disturbance

  • B Ling, D Novakovic, L Sulica
  • Journal:
    The Journal of Laryngology & Otology / Volume 128 / Issue 2 / February 2014
    Published online by Cambridge University Press:
    30 January 2014, pp. 209-211
    Print publication:
    February 2014
  • Objective:

    Although neurogenic cough is increasingly recognised, its pathophysiology remains obscure. We describe two cases of chronic cough following laryngeal herpes zoster, a rarely described manifestation of varicella-zoster virus reactivation, and suggest that this may be analogous to post-herpetic neuralgia. The same mechanisms may cause both phenomena.

    Case reports:

    We describe two cases of chronic cough persisting for more than three months following an acute attack of laryngeal herpes zoster.

    Conclusion:

    Neuronal damage by varicella-zoster virus results in irritable nociceptors and deafferentation, mechanisms known to cause post-herpetic neuralgia. When the vagus nerve is affected, as in laryngeal herpes zoster, the result may be a chronic cough. Similar damage may underlie chronic neurogenic cough in other contexts.