On February 6, 2023, a Mw 7.8 earthquake struck southern and central Turkey and northern and western Syria. Over 50 000 people were confirmed dead, and nearly 130 000 were injured. The Turkish government was leading the response there through coordination by the Disaster and Emergency Management Agency (AFAD). A massive search and rescue operation continued, and humanitarian partners were rapidly ramping up efforts to provide life-saving assistance. Over 53 000 Turkish emergency workers were deployed to the regions affected by the earthquakes. More than 100 nations and international organizations mounted a massive, unprecedented response. Among them, the State of Israel dispatched 2 missions, with the first on the ground the same day as the earthquake. Under guidance of the local health authorities, it was determined that the most effective approach would be to support an existing medical facility rather than establishing a standalone field operation. Teams responding to disaster zones should arrive only after a formal request and deploy after full coordination with the local country. The devastated country understands best what is really needed. Deploying in full collaboration has an advantage of better cultural understanding and long-term effect in restoring the local needs.