This article presents 19 lead seals from the Museum of Bergama (ancient Pergamon), dating from the early eighth to the early twelfth century. We offer a descriptive catalogue of these Middle and Late Byzantine seals preserved in a western Turkish museum. The owners of these seals were primarily ecclesiastical, legal or military dignitaries who were probably active in Pergamon, in southwestern Mysia, Aeolis or Lydia. The catalogue is followed by an appendix on a Byzantine magical amulet.