Herbicide-resistant weeds have impacted crop production throughout the United States, but the effect they have on extension programming has not been evaluated. In June 2007, 38 extension weed specialists throughout the United States, responded to a survey on herbicide-resistant (HR) weeds and the impact they are having on extension education programming. Survey results revealed that HR weeds have had a significant impact on extension programming particularly for agronomic crops. In the last 10 yr, agronomic weed specialists' extension programming was almost twice as likely to be impacted by the presence of HR weeds as compared to horticultural programming. In the next 5 yr, agronomic extension programming is twice as likely to be altered. Of 37 weed species reported, seven genera or species of weeds represented 80% of the major HR biotypes reported. These include Amaranthus species, horseweed, Setaria species, common lambsquarters, kochia, giant ragweed, and Lolium species. Five weed species (common ragweed, common lambsquarters, horseweed, kochia, and three foxtail species) exhibited weed by mode of action (MOA) interactions when evaluated as major or minor problems. Herbicide resistance problem severity differed for weed species, herbicide MOA, and crops. The results of this survey of university extension personnel confirm that HR weeds have impacted extension programming and will continue to impact programming in the future.