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1 results

  • 16 - The role of in vitro maturation of oocytes for anovulatory polycystic ovary syndrome

  • Edited by Adam Balen, University of Leeds, Stephen Franks, Roy Homburg, Sean Kehoe
  • Book:
    Current Management of Polycystic Ovary Syndrome
    Published online:
    05 July 2014
    Print publication:
    01 October 2010, pp 185-194

  • Summary

    A number of studies have shown that the presence of ovaries of polycystic morphology, regardless of whether there are additional features of the full polycystic ovary syndrome (PCOS), significantly increase the risk of developing moderate to severe ovarian hyperstimulation syndrome (OHSS). in vitro maturation (IVM) is an approach with the potential to increase both the simplicity and safety of assisted reproductive technology (ART) treatment through the absence of the need for ovarian stimulation. IVM is a promising technique for women with anovulatory PCOS. The success rates are currently lower than those achieved with in vitro fertilisation (IVF) but IVM is safer and easier to undertake for the woman and it avoids gonadotrophin stimulation and the attendant risk of OHSS. While IVM is apparently safer for the woman, long-term paediatric studies are required before IVM can be fully assessed, which is also the case for other ART treatments.