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apolipoproteína e

European Psychiatry Spanish edition (1)

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Frecuencia de la apolipoproteína E-ɛ4, en la esquizofrenia de déficit
F. Thibaut, A. Van der Elst, D. Campion, C. Martin, B. Coron, S. Dollfus, T. H. Frebourg, M. Petit
Journal:

European Psychiatry (Ed.Española) / Volume 7 / Issue 1 / February 2000

Published online by Cambridge University Press:

12 May 2020, pp. 41-44

Print publication:

February 2000
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Se ha encontrado que el genotipo de la apolipoproteína E (ApoE) afecta a la expresión de varios trastornos neuropsiquiátricos. Determinamos las frecuencias del genotipo de la ApoE y su relación con los síntomas negativos primarios en 61 pacientes esquizofrénicos sin déficit y 45 con déficit, y los comparamos con 98 sujetos de control. No se observaron diferencias cuando se compararon las frecuencias del genotipo o de los alelos entre los tres grupos. Nuestros datos no apoyan la existencia de un papel para la ApoE en la expresión fenotípica de la esquizofrenia.