In this paper, we define Swan conductors for unit-root overconvergent F-isocrystals using the theory of arithmetic 𝒟-modules due to Berthelot. Our Swan conductors are compared with the Swan conductors for ℓ-adic sheaves constructed by Kato and Saito using a geometric method. As an application, we prove the integrality of Swan conductors in the sense of Kato and Saito under the ‘resolution of singularities’ assumption.