Computed tomography angiography (CTA) and magnetic resonance angiography (MRA) are used instead of conventional angiography for many cases requiring evaluation of the blood vessels. This chapter discusses the indications, diagnostic capabilities, and limitations of CTA of the upper and lower extremities, followed by images of important pathological findings. CTA, like conventional angiography, should be performed after traumatic injuries in patients whose injured extremity is pulseless, has a neurological deficit, has an expanding hematoma, or has a bruit or thrill. It can be used to detect most vascular lesions, including thrombus, aneurysm, arteriovenous fistulas, and injury to the vessel wall. CTA is useful in detecting traumatic injuries, with specificities from 87% to 98%. Suitable images require multidetector scanners and appropriate reconstruction software. Since CTA is not performed in real time but produces static images, it may be difficult to delineate vascular occlusion and other vascular injuries from vasospasm.