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bacteria infection

Mathematical Modelling of Natural Phenomena (1)

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The Effect of Bacteria on Epidermal WoundHealing
E. Agyingi, S. Maggelakis, D. Ross
Journal:

Mathematical Modelling of Natural Phenomena / Volume 5 / Issue 3 / 2010

Published online by Cambridge University Press:

28 April 2010, pp. 28-39

Print publication:

2010
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Epidermal wound healing is a complex process that repairs injured tissue. The complexityof this process increases when bacteria are present in a wound; the bacteria interactiondetermines whether infection sets in. Because of underlying physiological problemsinfected wounds do not follow the normal healing pattern. In this paper we present amathematical model of the healing of both infected and uninfected wounds. At the core ofour model is an account of the initiation of angiogenesis by macrophage-derived growthfactors. We express the model as a system of reaction-diffusion equations, and we presentresults of computations for a version of the model with one spatial dimension.