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26 - Imaging carotid disease: MR and CT perfusion
from Monitoring the local and distal effects of carotid interventions
- By Jeroen van der Grond, Leiden University Medical Center, Leiden, The Netherlands, Matthias J. P. van Osch, Leiden University Medical Center, Leiden, The Netherlands
Edited by Jonathan Gillard, University of Cambridge, Martin Graves, University of Cambridge, Thomas Hatsukami, University of Washington, Chun Yuan, University of Washington
Book:

Carotid Disease

Published online:

03 December 2009

Print publication:

07 December 2006, pp 358-371
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Summary

Determination of the actual cerebral hemodynamical status at the tissue level in patients with carotid artery disease remains one of the potential methods to determine the risk for recurrent, hemodynamically induced, symptoms in patients with carotid artery disease. Magnetic resonance imaging (MRI) offers two different approaches to measure the cerebral perfusion. The first technique, arterial spin labeling (ASL), exploits the water in blood as an endogenous tracer. Dynamic susceptibility contrast MRI (DSC-MRI or MR bolus tracking) is the alternative method. This method uses an intravenous injection of contrast agent, applied as an exogenous tracer. Both techniques have been used to study the CBF in patients with stenotic artery disease, showing their ability to provide important information on the hemodynamic status. Perfusion computed tomography (CT) is useful to evaluate the hemodynamic state of patients with chronic major cerebral artery occlusive disorders.

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26 - Imaging carotid disease: MR and CT perfusion

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26 - Imaging carotid disease: MR and CT perfusion

Summary