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1 results

  • 1 - Learning and Memory in the Nematode Caenorhabditis elegans

  • from Part I - Evolution of Learning Processes
  • Edited by Mark A. Krause, Southern Oregon University, Karen L. Hollis, Mount Holyoke College, Massachusetts, Mauricio R. Papini, Texas Christian University
  • Book:
    Evolution of Learning and Memory Mechanisms
    Published online:
    26 May 2022
    Print publication:
    19 May 2022, pp 15-32
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  • Summary

    Caenorhabditis elegans is a microscopic, free-living nematode species that has been studied as a model organism for learning and memory. With a nervous system consisting of 302 neurons, its accessible anatomy accommodates an incredible capacity to support a wide range of behaviors to navigate in its surroundings. In this chapter, we review both the classic and cutting-edge studies on learning and memory in C. elegans. These findings illustrate that learning allows C. elegans to adaptively adjust its behaviors to the environment as a result of experiences and plays a key role in promoting the organism’s fitness. Learning and memory in simple organisms like C. elegans is mediated by complex neural and molecular mechanisms. Mechanisms of learning and memory elucidated from C. elegans studies show convergence onto the learning mechanisms discovered in other species, suggesting that a large portion of the neural principles of learning and memory are rooted in evolution.