This paper explores Christianity's ambiguous relationship to capitalism by engaging Marx's notion of the fetishism of commodities as a way of rethinking Marxism's critique of religion from the standpoint of political economy. Following Etienne Balibar's distinction between the theory of ideology and Capital's theory of fetishism, I examine how the later Marx conceived of religion as socially conditioned by the society of commodity production, which takes on religious dimensions. Commodities are the basis for a concept of fetishism which commands total subjection, alienating human beings under capitalism. This critical focus also reveals Christianity in its totalizing role as a symbolic structure shaped by the inescapable logic of exchange-value, money, and universal equivalents. Nonetheless, Christianity retains the impetus to anti-fetishism, provided it unites with the Marxist science of critical perception. This anti-fetishistic union focuses on the transparent and revolutionized social relations of real presence as the nonalienated reverse of fetishism's false presence. A critical apophaticism, tempered by the materialist amendments of Marika Rose and Slavoj Žižek, offers the bridge to such a union and highlights the anti-fetishistic avenues of failure and utopia.