Conjunctive item response models are introduced such that (a) sufficient statistics for latent traits are not necessarily additive in item scores; (b) items are not necessarily locally independent; and (c) existing compensatory (additive) item response models including the binomial, Rasch, logistic, and general locally independent model are special cases. Simple estimates and hypothesis tests for conjunctive models are introduced and evaluated as well. Conjunctive models are also identified with cognitive models that assume the existence of several individually necessary component processes for a global ability. It is concluded that conjunctive models and methods may show promise for constructing improved tests and uncovering conjunctive cognitive structure. It is also concluded that conjunctive item response theory may help to clarify the relationships between local dependence, multidimensionality, and item response function form.