Carfentrazone-ethyl is one of few herbicides labeled for control of silvery-thread moss (STM) in golf course putting greens, but common use rates are up to three times higher than for broadleaf weeds. Our objective was to determine the efficacy of a single POST application of carfentrazone-ethyl for STM control in greenhouse and field dose response studies. In the greenhouse, carfentrazone-ethyl was applied at 0, 14, 28, 56, 112, and 224 g ai ha–1 to pots containing established STM and creeping bentgrass. Percent gametophyte injury was visually estimated at 14, 28, 49, and 77 d after treatment (DAT). Shoot viability was determined by excising shoots from treated pots and plating them in Petri dishes containing sand. The 28- and 49-DAT ED90 (doses required to cause 90% gametophyte injury) were 26.8 and 54.3 g ha–1, respectively; both of these doses are substantially lower than the label rates for long- and short-term control, respectively. All doses reduced the viability of transplanted shoots at 10 DAT compared to untreated STM; however, regrowth occurred in all Petri dishes by 17 DAT. Field studies were initiated in Manhattan, KS and San Luis Obispo, CA to corroborate greenhouse results. Averaged across locations, carfentrazone-ethyl applied at 56 and 112 g ha–1 caused 76% and 84% STM injury at 14 DAT, but STM injury quickly lessened to 45% and 48% by 28 DAT, respectively. In greenhouse and field studies, STM recovery did not occur until 2 wk after treatment (WAT), which indicates the label-stipulated application interval of 2 wk is too short. Our research suggests that 56 g ha–1 can provide similar burndown control of STM as compared to the highest label rate (112 g ha–1), and turfgrass managers should consider extending the reapplication interval to 3 or 4 wk when moss recovery is observed.