Studies were conducted in conventional and no-tillage corn in 1990, 1991, and 1992 at Wooster, OH, to measure corn yield and velvetleaf seed production in response to density of early and late emerging velvetleaf, and to estimate economic thresholds. The percent reduction in corn yield fit a hyperbolic function over velvetleaf densities from 1 to 30 plants m2. The percent yield loss and velvetleaf seed production were higher in a warm, wet year (1990) than in a dry (1991) or cold, wet year (1992). The percent corn yield reduction was generally greater in no-tillage than in conventional tillage and from early rather than late emerging velvetleaf. Maximum velvetleaf seed production ranged from about 18,000 seeds m2 for early emerging weeds in no-tillage in 1990 to 100 seeds m2 for late emerging weeds in no-tillage in 1992. The single year economic threshold for early emerging velvetleaf ranged from 0.40 to 14.0 velvetleaf m2 in conventional tillage and 0.13 to 3.13 in no-tillage. Economic thresholds that were predicted using yield goal information deviated from actual thresholds (using actual yields) for a given year by −43 to 30%. Single year economic thresholds were similar in both tillage treatments, but their value for management decisions is questionable due to variation among growing seasons and weed seed production from subthreshold populations.