Economic decision rules for postemergence herbicide control of barnyardgrass in corn were developed. Damage and control functions that formed the basis of an economic model were estimated. Barnyardgrass density and time of emergence relative to the crop were fundamental to calculate the damage function. The control function described barnyardgrass dry weight response to variable doses of two herbicides. Both the biologist's and economist's weed control decision rules, derived from the economic model, were influenced by time of weed emergence relative to the crop, corn yield, and price. Inclusion of time of weed emergence relative to the crop improved our interpretative ability of derived decision rules. The biologist's threshold weed density was more sensitive to changes in parameter values than the economist's optimal herbicide dose strategy. Herbicide use with recommended label dose was greater than either the economically optimal or the biologically effective doses. Use of the biologically effective dose for postemergence weed control decisions was cost efficient and could be of practical significance to corn growers.