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2 results

  • Case 65 - A- or Paucisymptomatic HyperCKaemia

  • from Myopathies
  • Jessica E. Hoogendijk, University Medical Center Utrecht, Marianne de Visser, Amsterdam University Medical Center, Pieter A. van Doorn, Erasmus MC, University Medical Center, Rotterdam, Erik H. Niks, Leiden University Medical Center
  • Book:
    Neuromuscular Disease
    Published online:
    29 November 2024
    Print publication:
    19 December 2024, pp 266-268

  • Summary

    A 44-year-old man was referred because of hyperCKaemia (elevated CK activity). CK ranged from 1300 to 2200 IU/L (normal < 171). Before referral some investigations were performed. TSH was normal. HyperCKaemia was initially considered to be related to the use of simvastatin, but four months after withdrawal of this drug, CK was still markedly elevated.

    He did not complain about muscle weakness, muscle cramps, or myalgia. Previous history disclosed diabetes mellitus type 2, hypertension, and Asperger syndrome. Medication included metoprolol/hydrochlorothiazide, enalapril, and metformin. Family history was negative for neuromuscular disorders.