Cancer patients often have a variety of skin eruptions ranging from infections to irritant contact dermatitis. Reviewing gentle skin care and educating patients on potential side effects of various treatments, such as post-radiation dermatitis or vulvovaginal graft-versus-host disease, is beneficial. This chapter will focus on common vulvar conditions that may arise during cancer treatment such as infections (folliculitis, abscesses and furuncles, angioinvasive infections, herpesvirus and candidal infections), primary dermatoses (lichen sclerosus and lichen planus), and therapy side effects (genitourinary syndrome of menopause, lymphedema, acquired lymphatic anomaly, radiation dermatitis and recall, toxic erythema of chemotherapy, and immune-checkpoint inhibitor cutaneous toxicities). Additionally, considerations for vulvar biopsies are discussed.

The unique hormonal environment of pregnancy causes several changes to skin, hair, and nails. These changes may alter the appearance or behavior of chronic skin conditions, necessitating management changes. Additionally, the anesthesiologist may encounter several pregnancy-specific dermatologic conditions, some of which have broad implications for anesthetic management. Dermatologic drug safety in pregnancy is also a significant concern, as many of the medications commonly used outside of pregnancy are considered teratogenic. A thorough understanding of common dermatologic disease states and their implications on anesthetic management is crucial for the practitioner of obstetric anesthesia.