We prove existence and uniqueness for the solution of a class of mixed fractional stochastic differential equations with discontinuous drift driven by both standard and fractional Brownian motion. Additionally, we establish a generalized Itô rule valid for functions with an absolutely continuous derivative and applicable to solutions of mixed fractional stochastic differential equations with Lipschitz coefficients, which plays a key role in our proof of existence and uniqueness. The proof of such a formula is new and relies on showing the existence of a density of the law under mild assumptions on the diffusion coefficient.