This article deals with the estimation of inserted defects in bone material by photons used for radiation therapy, for instance, to treat carcinogenic diseases including bone cancer. However, there are side effects by radiation on structures of bones. Structure alters electron density of states that, in time, influences biomedical reactions on bone life condition. Exoelectron emission (EEE) phenomenon underlies a new electron spectroscopy to explore alteration of the electronic structurally dependence properties of bone material. The influence of photons with different energies and the dose rate on the bone structure is discussed. The bone EEE response is not linear on the dose rate and probably is connected with interaction of radiation induced centers responsible for EEE process. EEE structural changes have varied with energy variety of doses used in radiotherapy.