Field experiments were conducted to identify herbicides for selectively controlling foxtail barley seedlings in spring wheat and flax. ICIA0604, fenoxaprop-P/safener, CGA184927/safener, metribuzin, and MON37500 in wheat and sethoxydim, clethodim, quizalofop, fluazifop-P, and the mixture of fluazifop-P/fenoxaprop-P in flax were applied at the three- to four-leaf and one- to three-tiller stages of foxtail barley. MON37500 was the only herbicide tested in wheat that provided excellent control of foxtail barley and a high degree of crop tolerance. MON37500 at 13 to 19 g/ha applied at the early growth stage controlled foxtail barley but rates of 25 to 30 g/ha were needed at the later growth stage. In flax, quizalofop was the most efficacious herbicide on foxtail barley. Sethoxydim and clethodim sometimes provided weed control similar to that of quizalofop when applied at the three- to four-leaf stage, but quizalofop was always more effective at the one- to three-tiller stage of foxtail barley. Wheat and flax yields were greater when effective herbicides were applied at the early than at the late stage, indicating the need for early control of foxtail barley to minimize weed competition. MON37500 in wheat and quizalofop in flax provide growers with highly efficacious herbicide options for in-crop control of foxtail barley in conservation tillage systems.