The topic of gender blindness is increasingly gaining the attention of researchers. Even in fields that do not commonly engage with gender, gender blindness has been recognized as a factor that has potential to limit the validity of research findings. This article explores the prevalence and implications of gender blindness in quantitative research for political science outcomes. We first reanalyze three articles recently published in the American Journal of Political Science (AJPS) to illustrate the impact of gender blindness on quantitative research. Next, we classify all articles with quantitative methodology published in the AJPS in 2018 and 2019 by the degree of gender blindness in the research design. Our findings demonstrate how gender blindness impacts outcomes and estimate its prevalence in political science. They show that accounting for gender yields more accurate results and facilitates a better understanding of political behavior and phenomena.