In anticipation of space exploration where astronauts are traveling away from Earth, and for longer durations with an increasing communication lag, artificial intelligence (AI) frameworks such as large language learning models (LLMs) that can be trained on Earth can provide real-time answers. This emerging technology may be helpful for acute medical emergencies, particularly in austere and distant space environments. In this manuscript, we provide an overview of generative pre-trained transformer (GPT) technology, a rapidly emerging AI technology, and implications, considerations, and limitations of such technology for space health.

Novel concepts are essential for design innovation and can be generated with the aid of data stimuli and computers. However, current generative design algorithms focus on diagrammatic or spatial concepts that are either too abstract to understand or too detailed for early phase design exploration. This paper explores the uses of generative pre-trained transformers (GPT) for natural language design concept generation. Our experiments involve the use of GPT-2 and GPT-3 for different creative reasonings in design tasks. Both show reasonably good performance for verbal design concept generation.