Greenhouse studies were conducted to evaluate the effectiveness of Kinetic, a silicone adjuvant that appeared to increase the efficacy and rainfastness of the isopropylamine salt of glyphosate on velvetleaf, sicklepod, barnyardgrass, guineagrass, yellow foxtail, and yellow nutsedge. Simulated rainfall of 1.3 cm in 5 min at 15 and 60 min after herbicide treatment reduced glyphosate efficacy on all weeds. Kinetic enhanced glyphosate efficacy when yellow nutsedge and guineagrass were subjected to post-spray rainfall at 60 min. On velvetleaf, sicklepod, and yellow foxtail, Kinetic improved glyphosate efficacy when the critical rain-free period was reduced to 15 min. Kinetic failed to provide rainfastness for barnyardgrass, thereby indicating a specificity of Kinetic for certain weed species.