X-ray powder diffraction data, unit-cell parameters, and space group for inclusion complex of β-cyclodextrin with fraxinellone, C42H70O35·C14H16O3·3H2O, are reported [a = 19.294(2) Å, b = 26.639(1) Å, c = 16.467(3) Å, β = 110.451(9)°, cell volume V = 7930.34 Å3, Z = 4 and space group C2]. All measured lines were indexed and are consistent with the C2 space group. No detectable impurities were observed.