The relative efficacy of cognitive restructuring and interoceptive exposure
procedures for the treatment of panic disorder, as well as the differential
effects of the order of these interventions, was studied. Eighteen clients
with panic disorder were seen for four sessions of exposure therapy and four
sessions of cognitive therapy in a crossover design study. Half of the
participants received exposure therapy followed by cognitive therapy and for
half the order was reversed. There was a 1-month follow-up period between the two interventions and after the second intervention. Questionnaire
measures and independent clinician ratings were used to assess
outcome. Participants expected greater benefit from cognitive therapy, but
tended to improve to a similar degree with either intervention. The order in
which treatments were presented did not influence outcome. Participants
tended to improve with the first intervention and maintain improvement
across the follow-up periods and subsequent intervention. Several
methodological limitations qualify the conclusions that can be drawn from
this study. These limitations, as well as some conceptual and methodological
challenges of conducting this type of research, are discussed.