Aiming at reconstructing the prologue to On Nature, the first part of this chapter focuses on the collocation of the demonological fragments which, by expanding on Empedocles’ exile introduced in B 115, depict his katabasis into the realm of the dead. The narrative of this extraordinary journey serves Empedocles as authorial legitimation on matters beyond ordinary human knowledge. The second part of Chapter 2 reconstructs the rest of the proem by interweaving traditionally introductory themes, such as the dedication to Pausanias and the invocation to the Muse, with novel topics concerning the rejection of ritual sacrifice based on Empedocles’ concept of rebirth. The proem thus reconstructed presents a coherent programmatic structure and makes sense of several Empedoclean fragments that are essential for a comprehensive and impartial understanding of his thought. Moreover, by showing that religious concerns inform the entire introductory section, the new proem indicates that the concept of rebirth is central to Empedocles’ physical system and thus offers a new basis to rethink the interplay of myth, religion, and physics in his natural philosophy.

We are fortunate to have detailed descriptions of both the ritual and the suppliant’s experience at the sanctuary of Trophonius in Lebadeia that provide an opportunity for a case study juxtaposing ancient evidence with the results of modern research in cognitive science. The paper explores changes in the suppliant’s body and mind, experienced during his stay in Trophonius’ sanctuary.<break/>The main rite was a descent into the artificial subterranean cave of Trophonius, who was believed to appear to the suppliants in person. In the subterranean chamber the inquirer experienced alteration of consciousness, induced by sensory deprivation and comprising vortex and out-of-body experiences as well as hallucinations and the sensation of unmediated communication with supernatural beings. The core experience was preceded by a series of preliminary rites, each of them involving a different cognitive and/or physiological mechanism.<break/>The ritual of descent to Trophonius combined characteristics of a mystery rite, such as secrecy, brush with death, utter distress, obliteration of memory, and personality change, and an oracular consultation, which was based on interpretation of hidden knowledge revealed in the sacred grotto.