The problem of deciding whether a set of mental test data is consistent with any one of a large class of item response models is considered. The “classical” assumption of locla independence is weakened to a new condition, local nonnegative dependence (LND). Necessary and sufficient conditions are derived for a LND item response model to fit a set of data. This leads to a condition that a set of data must satisfy if it is to be representable by any item response model that assumes both local independence and monotone item characteristic curves. An example is given to show that LND is strictly weaker than local independence. Thus rejection of LND models implies rejection of all item response models that assume local independence for a given set of data.