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7 results

  • Chapter 8 - Vulvar Lesions and Eruptions

  • Edited by Laurie J. Mckenzie, University of Texas MD Anderson Cancer Center, Houston, Denise R. Nebgen, University of Texas MD Anderson Cancer Center, Houston
  • Book:
    Caring for the Female Cancer Patient
    Published online:
    23 October 2024
    Print publication:
    17 October 2024, pp 117-131

  • Summary

    Cancer patients often have a variety of skin eruptions ranging from infections to irritant contact dermatitis. Reviewing gentle skin care and educating patients on potential side effects of various treatments, such as post-radiation dermatitis or vulvovaginal graft-versus-host disease, is beneficial. This chapter will focus on common vulvar conditions that may arise during cancer treatment such as infections (folliculitis, abscesses and furuncles, angioinvasive infections, herpesvirus and candidal infections), primary dermatoses (lichen sclerosus and lichen planus), and therapy side effects (genitourinary syndrome of menopause, lymphedema, acquired lymphatic anomaly, radiation dermatitis and recall, toxic erythema of chemotherapy, and immune-checkpoint inhibitor cutaneous toxicities). Additionally, considerations for vulvar biopsies are discussed.

  • Chapter 4 - Vulval Disorders in Pregnancy

  • Edited by Swati Jha, Sheffield Teaching Hospital NHS Foundation Trust, Priya Madhuvrata, Sheffield Teaching Hospital NHS Foundation Trust
  • Book:
    Gynaecology for the Obstetrician
    Published online:
    14 July 2023
    Print publication:
    03 August 2023, pp 31-39

  • Summary

    Vulval disorders are not uncommon in obstetric practice. This chapter aims to enhance clinical skills in patient assessment, vulval examination and treatment of common benign vulval skin disease and infections. Basic treatments often benefit the patient (e.g. use of emollients and topical steroids). Some patients have complex disease and can present with more than one condition, so careful assessment and individualised management is essential. Understanding of when to refer onwards to a gynaecologist and even a vulval specialist service is important to optimise clinical outcomes.

  • Chapter 23 - Recurrent Vulvovaginitis

  • from Section 4 - Contraception and STIs
  • Edited by Tahir Mahmood, Charles Savona-Ventura, Ioannis Messinis, Sambit Mukhopadhyay
  • Book:
    The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology
    Published online:
    24 November 2021
    Print publication:
    02 December 2021, pp 182-185

  • Summary

    Recurrent vulvovaginitis (RVV) is a common gynaecological condition affecting women in all age groups. Different aetiological factors can present with similar symptoms and signs. It is important to identify the cause to provide the appropriate treatment.

    The three main causes include Candidiasis, bacterial vaginosis, and Trichomonas vaginalis. This is in addition to dermatological and hormone-dependent conditions such as erosive lichen planus, atrophic vaginitis and desquamative inflammatory vaginitis.

    Some risk factors for RVV have been identified; for example, diabetes, sex attitudes and hypoestrogenic state.

    Management of RVV may represent a challenge to healthcare professionals. It is important to realize the effect of the condition on the woman’s physical and psychological wellbeing, and the impact on their quality of life.

  • Efficacy of steroidal vs non-steroidal agents in oral lichen planus: a randomised, open-label study

  • A R Singh, A Rai, M Aftab, S Jain, M Singh
  • Journal:
    The Journal of Laryngology & Otology / Volume 131 / Issue 1 / January 2017
    Published online by Cambridge University Press:
    05 December 2016, pp. 69-76
    Print publication:
    January 2017
  • Objective:

    This study compared the therapeutic efficacy of steroidal and non-steroidal agents for treating oral lichen planus.

    Methods:

    Forty patients with clinical and/or histologically proven oral lichen planus were randomly placed into four groups and treated with topical triamcinolone, oral dapsone, topical tacrolimus or topical retinoid for three months. Pre- and post-treatment symptoms and signs were scored for each patient.

    Results:

    Patients in all treatment groups showed significant clinical improvement after three months (p < 0.05), with steroidal and non-steroidal agents having equal efficacy. Furthermore, of the non-steroidal drugs, oral dapsone had greater efficacy than topical retinoid (p < 0.05). However, no significant differences in outcome were recorded for oral dapsone vs topical tacrolimus (p > 0.05) and for topical retinoid vs topical tacrolimus (p > 0.05).

    Conclusion:

    Non-steroidal drugs such as dapsone, tacrolimus and retinoid are as efficacious as steroidal drugs for treating oral lichen planus, and avoid the side effects associated with steroids.

  • Lichen planus of the larynx

  • C E Rennie, R C Dwivedi, A S Khan, N Agrawal, W Ziyada
  • Journal:
    The Journal of Laryngology & Otology / Volume 125 / Issue 4 / April 2011
    Published online by Cambridge University Press:
    28 January 2011, pp. 432-435
    Print publication:
    April 2011
  • Objective:

    We report an extremely rare case of laryngeal lichen planus.

    Method:

    A case report and literature review of the aetiopathogenesis, clinical features and management of laryngeal lichen planus are presented.

    Results:

    A male patient presented with hoarseness and a history suggestive of squamous cell carcinoma of the larynx. However, characteristic histopathological findings demonstrated lichen planus. The patient responded very well to oral steroids, and at the time of writing had remained symptom-free for two years.

    Conclusion:

    This is the first English language report of laryngeal lichen planus. Lichen planus is a diagnosis of exclusion and responds well to steroids. However, patients should be followed up regularly as malignant change is known to occur.

  • Idiopathic, inflammatory, medial meatal, fibrotising otitis presenting with lichen planus

  • E Hopsu, A Pitkäranta
  • Journal:
    The Journal of Laryngology & Otology / Volume 121 / Issue 8 / August 2007
    Published online by Cambridge University Press:
    12 March 2007, pp. 796-799
    Print publication:
    August 2007
  • Background:

    Background: Of the acquired ear canal atresias, idiopathic, inflammatory, medial meatal, fibrotising otitis has been suggested as a distinct disease entity, for reasons of aetiology.

    Objective:

    To report three more cases of idiopathic, inflammatory, medial meatal, fibrotising otitis and to further consider the possible relationship between this condition and lichen planus.

    Patients:

    Three adult patients with idiopathic, inflammatory, medial meatal, fibrotising otitis, two with bilateral aural symptoms, treated and followed up at the department of otorhinolaryngology of Helsinki University Hospital.

    Results:

    We found idiopathic, inflammatory, medial meatal, fibrotising otitis, affecting solely the glabrous skin of the osseous part of the external ear canals, in three patients who also suffered from severe oral lichen planus.

    Conclusions:

    The aetiopathology or pathophysiology of idiopathic, inflammatory, medial meatal, fibrotising otitis may be linked with lichen planus. Early, active treatment of idiopathic, inflammatory, medial meatal, fibrotising otitis with local corticosteroids may prevent total medial meatal atresia.