As the Indigenous population in Canada ages, there is a need to recognize the role of place and culture in supporting health and resilience over the life course. This article draws on the findings of a Photovoice project about Southern Inuit experiences of transitions into aging and dementia in NunatuKavut, Labrador. Here, culture and the natural environment are prominent in descriptions of health promotion and care trajectories. These factors may contribute to healthy aging, protect against cognitive decline, and support the maintenance of identity for people living with dementia. However, significant pressures on ways of living embedded in the land are also evident. Such forces are impacting Southern Inuit older adults’ ability to age and be cared for “in place”. The findings of this research reflect a need to consider ways to support Southern Inuit older adults to age in place, which might include reflecting on culturally grounded understandings of personhood, and policy and programming which promote engagement with the nature and culture.