In this paper, an ultra-compact implantable antenna for biomedical applications is proposed. The proposed implanted meandered compact patch antenna is implanted inside the body at a depth of 2 mm. The proposed antenna was designed with Roger RO3003 (ɛr = 3) as substrate with an overall size of dimensions 5 × 5 × 0.26 mm3. The radiating element is a square patch antenna with different size rectangular slots and coaxial feeding. The proposed implantable antenna resonates at 2.45 GHz (from 2.26 to 2.72 GHz) frequency with a bandwidth of 460 MHz and a gain of −22.6 dB. The specific absorption rate has been considered for health care considerations, and the result is within the limits of the federal communication commission. The measured and simulated scattering parameters are compared, and good agreements are achieved. The proposed antenna is simulated and investigated for biomedical applications suitability.