This essay introduces the roundtable, “John R. Lewis's Legacies in Law and Religion.” A civil rights icon and long-standing US congressman representing Georgia's Fifth Congressional District, Lewis was often described as the moral conscience of the US Congress and the nation. The essays in this roundtable explore the many facets of Lewis's moral leadership, with particular attention to his influence on law and religion. This roundtable is a testament to what it means to speak up, speak out, and be bold in defense of justice.