In this paper, a novel SIW microwave sensor is designed to accurately determine the broadband complex permittivity of medium loss and dispersive liquids using a number of higher order modes in 11–20 GHz. To achieve a higher accuracy in characterization, the sensor is equipped with some methods such as Photonic Band Gap method, slow-wave via, and a new feedline, which enhances the quality factor for the higher order TE1,0,n modes. The operating principle of this sensor is based on the cavity perturbation technique, in which the resonant properties of the cavity are utilized to extract the dielectric properties of liquid under test. To provide a method to decrease the LUT consumption, a winding microfluidic channel is designed and embedded in the cavity. The channel increases the interaction between the induced electric field and the LUT. The accuracy of different perturbation technique for determination of permittivity is compared with each other.