Typically most studies of individual employees perceptions of the work place adopt multiple regression models (ordinary least squares [OLS]) which ignore inherent clustering in their data. However, such an approach does not supply unbiased and accurate answers to research questions. This study intends to simulate three data alternatives – weighted, disaggregated (individual level), and aggregated (organizational level) using the OLS and multilevel models to compare the results of different research designs. To answer the research questions, the current study investigates the impact of individual and organizational factors on job satisfaction, using a 2000 USA National Partnership for Reinventing Government survey. This study presents the methodological misuse and measurement errors of the previous research and presents guidelines for future research.