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1 results

  • 15 - Current clinical trials in ovarian cancer

  • from SECTION 4 - WHAT QUESTIONS ARE BEING ASKED BY CURRENT CLINICAL TRIALS?
  • Edited by Sean Kehoe, Richard J. Edmondson, Martin Gore, Iain A. McNeish
  • Book:
    Gynaecological Cancers
    Published online:
    05 February 2014
    Print publication:
    01 June 2011, pp 205-222

  • Summary

    Epithelial ovarian cancer (EOC) is the most common cause of death among women who develop gynaecological cancer and the fifth most common cause of cancer related death in females in Western countries. The value of the neoadjuvant approach in the primary treatment of advanced EOC is currently one of the most debated issues in gynaecological oncology worldwide. The disease-free interval, number of recurrence sites, patient's performance status, surgical outcome of the primary surgery and current amount of ascites have been discussed as possible predictive factors of clinical outcome in surgery at recurrence. Anti-angiogenic therapy represents huge effort in translational research, with high expectations from investigators and patients alike. The proliferation of clinical trials in ovarian cancer reflects the focus and determination of investigators internationally and many promising hypotheses are being explored within the international collaborative efforts.