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The unique hormonal environment of pregnancy causes several changes to skin, hair, and nails. These changes may alter the appearance or behavior of chronic skin conditions, necessitating management changes. Additionally, the anesthesiologist may encounter several pregnancy-specific dermatologic conditions, some of which have broad implications for anesthetic management. Dermatologic drug safety in pregnancy is also a significant concern, as many of the medications commonly used outside of pregnancy are considered teratogenic. A thorough understanding of common dermatologic disease states and their implications on anesthetic management is crucial for the practitioner of obstetric anesthesia.
Cardiovascular disease (>25%) is the leading cause of death among pregnant women in the United States. This chapter covers risk stratification, pathophysiology, and anesthetic management of women with specific cardiac diseases. In the last decade, advances in treatment and management of cardiac disease in the pregnant patient have led to improvements in survival of obstetric patients with known cardiac disease. Key to the improvements in care is the creation of Pregnancy Heart Teams, multidisciplinary teams with knowledge and experience caring for the obstetric patient with cardiovascular disease. Cardiovascular disease encompasses a heterogeneous group of lesions with differing hemodynamic goals, management and risks during pregnancy, delivery, and postpartum. The anesthesiologist is best able to care for these women by understanding the specific cardiovascular lesion, a woman’s current status, the obstetric and fetal considerations and the impact of anesthetic techniques.
Pregnant women may have chronic neurological disease or may develop neurological disease during pregnancy and the postpartum period. Status epilepticus, stroke, cerebral vein thrombosis, posterior spinal encephalopathy syndrome (PRES), are some neurological conditions that are more likely to occur during pregnancy. Clinical trials of PRES treatment are lacking. Intensive care is usually indicated, with continuous blood pressure monitoring, treatment of hypertension, and if possible, removal of the underlying cause. Both neuraxial (including both spinal and epidural anesthesia/analgesia) and general anesthesia have been described for delivery of patients with Guillain-Barre syndrome. High thoracic or cervical spinal cord lesions are associated with neurogenic shock because of blockade of autonomic function at the level of the spinal cord injury (SCI). Spinal/epidural hematoma is a rare complication of neuraxial procedures in the obstetric population. Pregnant patients are hypercoagulable and this may confer some degree of protection.
This chapter provides an overview of the normal changes in coagulation associated with pregnancy. It discusses the most common challenges experienced by anesthesiologists in the coagulopathic pregnant woman. The result is a hypercoagulable state that maintains placental function during pregnancy and protects the parturient from hemorrhagic complications during delivery but increases the risk of thromboembolism. The risks of neuraxial anesthesia in the coagulopathic parturient must be weighed against the risks of the alternatives and the gravity of the situation. Normal pregnancy imparts an increased tendency toward thrombus formation, extension, and stability. Epidural or spinal hematoma are rare and devastating complications of neuraxial anesthesia in parturients. Their occurrence is almost invariably associated with clinical coagulopathy or the use of anticoagulants. Decisions regarding the most appropriate anesthetic management for obstetric patients can be difficult and fraught with pitfalls.
This chapter reviews the use of regional anesthesia techniques in obese patients. The most extensive experience with regional anesthetic techniques in obese patients is with neuraxial anesthesia. Obese patients require less local anesthetic than their normal counterparts to achieve a similar sensory level. For a lumbar approach for either an epidural or spinal anesthetic, a cooperative patient can be asked to identify the "midpoint of your body". The incidence of complications with epidural anesthesia increases with increasing weight. As with epidural anesthesia, obesity is an important factor influencing spinal anesthesia. Neuraxial anesthesia is often used in combination with general anesthesia during surgery to reduce the amount of inhalational and intravenous agents. All peripheral nerve blocks were performed using a nerve stimulator technique. Overweight and obese patients should not be excluded from undergoing regional anesthesia in the ambulatory setting.
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