How native (L1) and non-native (L2) readers utilise syntactic constraints on linguistic dependency resolution during language comprehension is debated, with previous research yielding mixed findings. To address this discrepancy, we report two large-scale studies, using self-paced reading and grammaticality judgements, investigating subject-verb agreement and reflexives in L1 English speakers and Arabic learners of L2 English. We manipulated sentence grammaticality and the properties of ‘distractor’ constituents (The key(s) to the cabinet(s) were rusty) in two studies testing number in agreement and gender/number in reflexives. Study 1 showed that L2ers’ performance largely patterned with L1ers’. Although grammaticality effects were smaller for agreement in L2ers than in L1ers, proficiency modulated L2 performance. Study 2 revealed no significant between-group differences. Contrasting some L1 studies, significant distractor effects were only detected for reflexives in Study 1. Together, these results imply that L2ers compute syntactic dependencies similarly to L1ers, and potential differences might be driven by L2 proficiency.