The paper outlines several approaches for dealing with meta-analyses of count outcome data. These counts are the accumulation of occurred events, and these events might be rare, so a special feature of the meta-analysis is dealing with low counts including zero-count studies. Emphasis is put on approaches which are state of the art for count data modelling including mixed log-linear (Poisson) and mixed logistic (binomial) regression as well as nonparametric mixture models for count data of Poisson and binomial type. A simulation study investigates the performance and capability of discrete mixture models in estimating effect heterogeneity. The approaches are exemplified on a meta-analytic case study investigating the acceptance of bibliotherapy.

The assumptions underlying item response theory (IRT) models may be expressed as a set of equality and inequality constraints on the parameters of a latent class model. It is well known that the same assumptions imply that the parameters of the manifest distribution have to satisfy a more complicated set of inequality constraints which, however, are necessary but not sufficient. In this paper, we describe how the theory for likelihood-based inference under equality and inequality constraints may be used to test the underlying assumptions of IRT models. It turns out that the analysis based directly on the latent structure is simpler and more flexible. In particular, we indicate how several interesting extensions of the Rasch model may be obtained by partial relaxation of the basic constraints. An application to a data set provided by Educational Testing Service is used to illustrate the approach.