Herbicides and interim summer crop treatments were studied in 1984 to 1987 to replace fungal endophyte-infected with endophyte-free tall fescue or red clover to improve forage quality. Foliar glyphosate or paraquat were applied in spring across interim crops with PRE herbicides. The interim crops, grain sorghum with atrazine, sorghum-sudangrass hybrid with metribuzin, or soybean with imazaquin, were each applied as confounded treatments across glyphosate or paraquat. Within an interim crop system, a follow-up glyphosate treatment was serially applied the next fall or spring. Then either red clover or endophyte-free tall fescue was spring drilled within the fall or spring glyphosate follow-up treatments. Glyphosate controlled old tall fescue better than paraquat, and improved the stand of the endophyte-free tall fescue. Control of tall fescue was 97% from 1.7 kg ai/ha glyphosate. Glyphosate reduced the endophyte from a 77% original infection level to 20% over all interim crops after drilling the endophyte-free tall fescue. Among interim crops, grain sorghum or the sorghum-sudangrass hybrid was more competitive than soybean with the uncontrolled tall fescue. Replacement with endophyte-free tall fescue was best in grain sorghum or sorghum-sudangrass hybrid stubble the next spring. Grain sorghum or sorghum-sudangrass hybrid following foliar glyphosate or paraquat treatment of endophyte-infected tall fescue reduced endophyte infection level in tall fescue to 28%. A follow-up fall treatment with glyphosate controlled tall fescue better than the spring retreatment and red clover and endophyte-free tall fescue were established better from fall retreated glyphosate. Red clover was easily established by drilling into the sod after treating endophyte-infected tall fescue with either glyphosate or paraquat.