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5 - Technical introduction to MRI
- By Rohit Sood, Michael Moseley
Edited by Stephen Davis, Marc Fisher, National Institute of Mental Health, Bethesda, Maryland, Steven Warach, National Institutes of Health, Baltimore
Book:

Magnetic Resonance Imaging in Stroke

Published online:

26 August 2009

Print publication:

20 March 2003, pp 55-68
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Summary

This chapter outlines the basic physical principles of magnetic resonance imaging (MRI), and overviews the MR techniques that have been developed for investigating stroke patients. Magnetic resonance angiography (MRA) is a major advance in application of MRI to imaging of patient blood flow in vessels. The signal intensity in MRI depends on proton density, T1, T2 and T2 relaxation process of any ensemble of the spins. Diffusion- and perfusion-weighted imaging combined with fast imaging capabilities on commercial systems has revolutionized our understanding of the pathophysiological mechanisms involved in the many clinical conditions especially cerebral ischemia and stroke. Another popular technique used for perfusion MR imaging is the arterial spin labelling (ASL). Magnetic resonance spectroscopy (MRS) of the brain is a noninvasive MR technique that gives the relative concentration of certain chemical compounds within 2 to 3 cm3 of tissue.