Research on anti-plastics activism in Indonesia and Malaysia, although increasing somewhat in recent years, is sparse and patchy. Interviews with local activists and a review of the existing literature, however, does suggest this activism is intensifying. Activists are educating people of the health and ecological risks of plastics, and operating nonprofit organizations to recycle and repurpose plastics. They are organizing cleanups and advocating for marginalized waste workers. And they are lobbying governments for stricter regulations, exposing illegal operations, and building transnational advocacy networks. Collectively, these strands of activism appear to have the potential to aggregate eco-actions and decrease plastic pollution. In the coming years, however, given the power of the global plastics industry and the nature of politics within Indonesia and Malaysia, pro-plastics corporations and industry allies are likely going to increasingly contest anti-plastics narratives and strive to undermine efforts to address the root causes of plastic pollution, including rising sales of single-use plastics by transnational corporations, the dumping and burning of unrecyclable plastics from high-income countries, and inadequate waste infrastructure and regulatory enforcement. Further research on how this politics is affecting the power and effectiveness of anti-plastics activism, the article concludes, is going to be essential for improving plastics governance.