Drawing on interviews, published sources and archival documents, this article examines Cuba's policy towards Latin America after Ernesto ‘Che’ Guevara's death. It argues that as a result of this event and other setbacks in the region, Cuba reconceptualised its priorities, de-emphasised armed revolution and embraced new revolutionary processes. The results were mixed. By the mid-1970s, Havana was more disillusioned about revolutionary prospects in Latin America than ever before. However, it had also rejoined the inter-American system after more than a decade of isolation. This article asks how, why and with what consequences for Fidel Castro's stated pledge to ‘make revolution’ these shifts in Cuba's Latin American relations took place.