Animals should have the capacity to adapt to changing environmental pressures to ensure sustainable productivity. The easier an animal can adapt to disease burdens without extra cost to the farmer, the more profitable the enterprise becomes. Effective immune response protects organisms against disease insults and contributes to improved productivity. Primary immune response of Ghanaian local, Sasso T-44 and broiler chickens to sheep red blood cell (SRBC) antigens was measured 5 days post-inoculation. Antibody levels were determined by haemagglutination. Local ecotypes and Sasso T-44 chicken were superior to broilers in terms of their ability to respond to antigens. Female chickens produced more antibodies in response to increased concentration of SRBC antigens while the opposite was true in the male population. Further investigation of the genetic correlation between production performance and immune response of various chicken breeds will help establish the effect of, for example, high growth rate of broilers on their immunological status.
