We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
A three-month-old boy was seen at the outpatient clinic because of reduced spontaneous movements, which his parents had noticed for a few weeks. His legs lay to the side, he barely moved his hands, and his parents had to increasingly support his head when feeding him. For the past two weeks. drinking became slower. He also drank less and he choked daily. Coughing and crying had become weak compared with the first two months of life. Pregnancy, birth, and family history were unremarkable. He was the second child of unrelated parents and had one healthy sister who was three years old.
A 27-year-old woman consulted the neurology clinic because of progressive muscle weakness in legs and arms. She noticed increasing difficulty in walking, with a maximum walking time of 15 minutes when there was a slight upwards slope, climbing stairs, and lifting heavy things. She had more and more frequent falls in which it felt like her legs suddenly could not bear her weight anymore. Once she fell, she wasn’t able to get up from the floor without help. At the time of referral, she also experienced problems rising from a sitting position. She also mentioned problems with repeated movements due to fatigability, for example, when she walked or was cleaning out the dishwasher.
In retrospect, she remembered that she had had a ‘typical’ walk from the age of five and had never been able to run. A subtle tremor of her fingers was already present in kindergarten. Her medical history was otherwise unremarkable. She had two healthy siblings.
A 33-year-old-woman who was diagnosed with chronic fatigue syndrome several years ago noticed a ‘heavy feeling’ and progressive weakness of the upper legs over a period of four months. Climbing stairs became very difficult, and eventually she could no longer walk independently. She did not complain about weakness in her arms. There were no sensory complaints. During the past months, her voice had changed. Especially if she was tired, she would speak ‘like a drunk’. There were no complaints about double vision, drooping eyelids, or swallowing. There were no clear symptoms of autonomic dysfunction. She did not drink alcohol but had smoked at least a pack of cigarettes per day for over 10 years.
Recommend this
Email your librarian or administrator to recommend adding this to your organisation's collection.