This paper presents an investigation on the self-focusing of a cosh-Gaussian laser beam in the thermal quantum plasma (TQP) by taking into account the effects of relativistic nonlinearity. An appropriate nonlinear Schrödinger equation has been solved analytically by applying the variational approach. The self-focusing and the self-phase modulation are examined under a variety of parameters. The self-trapping of a cosh-Gaussian laser beam is further studied at various values of the decentered parameter, b with different absorption levels, ${k}^{\prime}_i$. Numerical analysis shows that these parameters play a vital role in propagation characteristics. The significant contribution of the quantum effects to enhance the self-focusing and minimize the longitudinal phase has been observed. Further, a comparison has been made with the classical relativistic (CR), the relativistic cold quantum (RCQ), and the thermal quantum (TQ) regimes. The self-focusing is found to occur earlier and is strongest for the case of TQP in the present analysis.