This article questions the value of the categories ‘the school of Antioch’ and ‘Antiochene christology’ on the basis of the significant theological differences between the two central figures in the school: John Chrysostom and Theodore of Mopsuestia, both of whom studied together at the school of Diodore of Tarsus in the late fourth century. Drawing on scholarship which has pointed to the coherence of Theodore's exegesis and christology, I show that Chrysostom's exegesis and christology are also coherent, but in a way which is at odds with those of Theodore. As opposed to Theodore's distinctions between the two testaments and between the human and the divine in Christ, Chrysostom has a strongly unitive reading of scripture's two testaments and of the person of Christ. In my argument I especially employ Theodore's and Chrysostom's respective exegetical works on the Gospel of John.