Reaction-diffusion equations with degenerate nonlinear diffusion are in widespread use asmodels of biological phenomena. This paper begins with a survey of applications toecology, cell biology and bacterial colony patterns. The author then reviews mathematicalresults on the existence of travelling wave front solutions of these equations, and theirgeneration from given initial data. A detailed study is then presented of the form ofsmooth-front waves with speeds close to that of the (unique) sharp-front solution, for theparticular equation ut =(uux)x + u(1− u). Using singular perturbation theory, the author derives anasymptotic approximation to the wave, which gives valuable information about the structureof smooth-front solutions. The approximation compares well with numerical results.