Field trials were conducted in Georgia and South Carolina in 2000 and 2001 to evaluate the effects of glyphosate, diflubenzuron, and boron combinations on crop injury and soybean yield. No interactions among glyphosate, diflubenzuron, and boron were observed. Both glyphosate and boron caused significant foliar injury (chlorosis and leaf burn) ranging from 7 to 10% in one of three locations. Diflubenzuron did not cause significant soybean injury at any location. Soybean injury symptoms observed in these experiments were transient and did not negatively affect yield.