Sulfometuron at 17 g ai/ha in the planting furrow (13% of the anticipated fallow-field application rate) inhibited sugarcane emergence and development and ultimately reduced sugar yields in the initial production year by 13% when compared to a weed-free control that contained no herbicide in the planting furrow. Residual levels of metribuzin in the planting furrow representing 100% of the standard fallow-field application rate of 1,680 g ai/ha had no adverse effect on sugarcane development or sugar yield. When applied only to the soil surface immediately after planting, sulfometuron did not injure sugarcane, and sugar yields were equivalent to standard, at-planting, preemergence (PRE) applications of either metribuzin at 2,020 g/ha or a mixture of pendimethalin plus atrazine each at 2,240 g ai/ha. To minimize sugarcane injury, sulfometuron should be kept out of the germinating zone of lateral buds along planted sugarcane stalks.